Baldwin was 11-of-18 shooting with three 3-pointers and seven assists before leaving with 1:44 remaining after he was inadvertently struck in the face by Creightons Damien Jefferson going for a rebound.
Joey Brunk, a 6-foot-11 sophomore making his first start, added 13 points and Nate Fowler had three 3-pointers and 11 points for the Bulldogs (10-5, 1-1 Big East), who improved to 8-1 at home after shooting 51 percent.
Martin Krampelj had 16 points and eight rebounds to lead the Blue Jays (10-5), who had a three-game win streak snapped after shooting just 26 percent from the arc (7 of 27) and being outscored 40-28 in the paint. Mitch Ballock added 13 points and Davion Mintz 10.
Ty-Shon Alexander, Creightons leading scorer at 17.3 points per game, was just 1 of 10 from the arc, 3 of 13 overall and finished with nine points.